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Rabbit Anti-TFF2/PE-Cy5.5 Conjugated antibody (bs-23857R-PE-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-23857R-PE-Cy5.5
英文名称 Rabbit Anti-TFF2/PE-Cy5.5 Conjugated antibody
中文名称 PE-Cy5.5标记的三叶肽因子2抗体
别    名 Trefoil factor2; mSP; SP; Spasmolytic polypeptide; Spasmolysin; SML 1; SML1; spasmolytic protein 1; TFF 2; trefoil factor 2 (spasmolytic protein 1); TFF 2; TFF2_HUMAN; Trefoil factor 2; Trefoil factor 2 precursor.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,  (predicted: Rat, Pig, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12/14kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TFF2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Function:
Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity).

Subcellular Location:
Secreted.

Tissue Specificity:
Stomach.

Similarity:
Contains 2 P-type (trefoil) domains.

Database links:
Entrez Gene: 7032 Human

Omim: 182590 Human

SwissProt: Q03403 Human

Unigene: 2979 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

三叶肽可能使黏膜凝胶产生更大的稳定性,使胃黏膜对各种损伤因子的防御能力增强。三叶肽在诱导上皮修复上的直接作用,可用于许多胃肠道疾病。它作为辅助剂或取代皮质类固醇或其他免疫抑制剂,在溃疡病及炎症性肠病的治疗上可能是一个突破。
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