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Mouse Anti-Myc tag/AP Conjugated antibody (bsm-33024M-AP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bsm-33024M-AP
英文名称1 Mouse Anti-Myc tag/AP Conjugated antibody
中文名称 碱性磷酸酶(AP)标记的Myc tag标签单克隆抗体
别    名 avian myelocytomatosis viral oncogene homolog; bHLHe39; c-Myc; class E basic helix-loop-helix protein 39; MRTL; MYC; Myc Epitope Tag; myc proto-oncogene protein; myc-related translation/localization regulatory factor; oncogene c-Myc; proto-oncogene c-Myc; protooncogene homologous to myelocytomatosis virus; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog (avian).  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 标签抗体 
研究领域
抗体来源 Mouse
克隆类型 Monoclonal
克 隆 号 7D6
交叉反应 Recombinant protein
产品应用 WB=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性    状 Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated C-EQKLISEEDL
亚    型 IgG1
纯化方法 affinity purified by Protein G
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Epitope tags are useful for the labeling and detection of proteins using immunoblotting, immunoprecipitation and immunostaining techniques. Due to their small size, they are unlikely to affect the tagged protein's biochemical properties. The Myc epitope tag is widely used to detect expression of recombinant proteins in bacteria, yeast,insect and mammalian cell systems.

The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.

Subcellular Location:
Nucleus.

Database links:

Entrez Gene: 4609 Human

Entrez Gene: 17869 Mouse

Entrez Gene: 24577 Rat

Omim: 190080 Human

SwissProt: P01106 Human

SwissProt: P01108 Mouse

SwissProt: P09416 Rat

Unigene: 202453 Human

Unigene: 2444 Mouse

Unigene: 12072 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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