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Rabbit Anti-Somatostatin Receptor 5/FITC Conjugated antibody (bs-20418R-FITC)
~~~促销,代码KT202502A~~~
~~~促销,代码KT202502B~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-20418R-FITC
英文名称 Rabbit Anti-Somatostatin Receptor 5/FITC Conjugated antibody
中文名称 FITC标记的生长抑素受体5抗体
别    名 somatostatin receptor 5; SS5R; Somatostatin receptor subtype 5; Somatostatin receptor type 5; SS 5R; SS5 R; SST R5; SSTR 5; SSTR5; SS-5-R; SS5-R; SS5R; SSR5_MOUSE.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞膜受体  G蛋白偶联受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Mouse, Rat, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Somatostatin Receptor 5
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010]

Function:
Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 20609 Mouse

Entrez Gene: 25354 Rat

SwissProt: O08858 Mouse

SwissProt: P30938 Rat

Unigene: 353282 Mouse

Unigene: 91342 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

SSTR5为G-蛋白偶联的细胞膜受体,SSTR5的表达与肿瘤的分布、发生和发展中起重要作用。
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