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Rabbit Anti-RALGPS2/BF647 Conjugated antibody (bs-21178R-BF647)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-21178R-BF647
英文名称 Rabbit Anti-RALGPS2/BF647 Conjugated antibody
中文名称 BF647标记的RALGPS2蛋白抗体
别    名 dJ595C2.1; FLJ10244; FLJ25604; KIAA0351; Ral A exchange factor RalGPS2; Ral GEF with PH domain and SH3 binding motif 2; RALGPS 2; ras-specific guanine nucleotide-releasing factor RalGPS2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RALGPS2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
RalGPS2 (Ral GEF with PH domain and SH3 binding motif 2) is a guanine nucleotide exchange factor for RalA GTPase. It is expressed in testis and brain.

Function:
Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity).

Subunit:
Interacts with the SH3 domains of GRB2 and PLCG1. Interacts with RALA.

Subcellular Location:
Cell Membrane and Cytoplasmic. Associates with membranes through the PH domain.

DISEASE:
RALGPS2 is a potential candidate gene for susceptibility to Alzheimer disease linked to 1q24.

Database links:

Entrez Gene: 424429 Chicken

Entrez Gene: 457549 Chimpanzee

Entrez Gene: 100052879 Horse

Entrez Gene: 55103 Human

Entrez Gene: 78255 Mouse

Entrez Gene: 304887 Rat

Entrez Gene: 717165 Rhesus monkey

Entrez Gene: 779506 Xenopus tropicalis

Entrez Gene: 393446 Zebrafish

SwissProt: Q5ZJK0 Chicken

SwissProt: Q4R7W3 Cynomolgus Monkey

SwissProt: Q86X27 Human

SwissProt: Q9ERD6 Mouse

Unigene: 632485 Human

Unigene: 28376 Mouse

Unigene: 224486 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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