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Rabbit Anti-Cytohesin 3/Cy7 Conjugated antibody (bs-20269R-Cy7)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-20269R-Cy7
英文名称 Rabbit Anti-Cytohesin 3/Cy7 Conjugated antibody
中文名称 Cy7标记的胞粘蛋白3抗体
别    名 CYTH3; ARF nucleotide-binding site opener 3; ARNO3; ARNO3 protein; CYH3_HUMAN; Cyth3; Cytohesin-3; General receptor of phosphoinositides 1; Grp1; PH; PH, SEC7 and coiled-coil domain-containing protein 3; Protein ARNO3; PSCD3; SEC7 and coiled-coil domain-containing protein 3; SEC7 homolog C; Sec7-3; Sec7c.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  细胞粘附分子  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep, )
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cytohesin 3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008]

Function:
Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF through replacement of GDP with GTP.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Almost absent from liver, thymus and peripheral blood lymphocytes.

Similarity:
Contains 1 PH domain.
Contains 1 SEC7 domain.

Database links:

Entrez Gene: 9265 Human

Entrez Gene: 19159 Mouse

Entrez Gene: 116693 Rat

Omim: 605081 Human

SwissProt: O43739 Human

SwissProt: O08967 Mouse

SwissProt: P97696 Rat

Unigene: 487479 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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