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Rabbit Anti-TZFP/ZNF538/BF647 Conjugated antibody (bs-8007R-BF647)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-8007R-BF647
英文名称1 Rabbit Anti-TZFP/ZNF538/BF647 Conjugated antibody
中文名称 BF647标记的范可尼综合征相关锌指蛋白抗体
别    名 FANCC interacting protein; FANCC-interacting protein; Fanconi anemia zinc finger protein; FAXF; FAZF; OTTHUMP00000045790; repressor of GATA; Rog; Testis zinc finger protein; ZBT32_HUMAN; Zbtb32; ZBTB32 protein; Zinc finger and BTB domain containing 32; Zinc finger and BTB domain-containing protein 32; Zinc finger protein 538; ZNF538.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 转录调节因子  锌指蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Cat, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TZFP/ZNF538
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 Function:
DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T cells.

Subunit:
Homodimer (via PTB domain). Interacts with the N-terminal of FANCC. Interacts with ZBTB16. Interacts with GATA3 (By similarity).

Subcellular Location:
Nucleus. Located in nuclear speckles.

Tissue Specificity:
Predominantly expressed in testis. Some isoforms are ubiquitously expressed.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 1 BTB (POZ) domain.
Contains 3 C2H2-type zinc fingers.

Database links:

Entrez Gene: 27033 Human

Entrez Gene: 58206 Mouse

Entrez Gene: 688845 Rat

Omim: 605859 Human

SwissProt: Q9Y2Y4 Human

SwissProt: Q9JKD9 Mouse

Unigene: 99430 Human

Unigene: 116789 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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