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Rabbit Anti-Arc1/BF594 Conjugated antibody (bs-10793R-BF594)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-10793R-BF594
英文名称1 Rabbit Anti-Arc1/BF594 Conjugated antibody
中文名称 BF594标记的ARC1抗体
别    名 Dmel_CG12505; anon-WO0153538.31; anon-WO0153538.40; anon-WO0153538.41; anon-WO0153538.43; anon-WO0153538.45; Arc; CG12505; dArc1; dARC1; Dmel\CG12505; Activity-regulated cytoskeleton associated protein 1; CG12505 gene product from transcript CG12505-RA; CG12505-PA; Arc1-PA.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 昆虫  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Fruit Fly, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Fruit Fly Arc1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Arc, for activity-regulated cytoskeleton-associated protein (also known as Arg3.1), is a plasticity protein first characterized in 1995. Arc is a member of the immediate-early gene (IEG) family, a rapidly activated class of genes functionally defined by their ability to be transcribed in the presence of protein synthesis inhibitors. Arc mRNA is localized to activated synaptic sites in an NMDA receptor-dependent manner, where the newly translated protein is believed to play a critical role in learning and memory-related molecular processes. Arc is widely considered to be an important protein in neurobiology because of its activity regulation, localization, and utility as a marker for plastic changes in the brain. Dysfunctions in the production of Arc protein has been implicated as an important factor in understanding of various neurological conditions including: Amnesia; Alzheimer's disease; Autism spectrum disorders; and, Fragile X syndrome. Along with other IEGs such as zif268 and Homer 1a, Arc is also a significant tool for systems neuroscience as illustrated by the development of the cellular compartment analysis of temporal activity by fluorescence in situ hybridization, or catFISH technique (see fluorescent in situ hybridization).

Database links:

SwissProt: Q7K1U0  Fruit Fly

Entrez Gene: 36595  Fruit Fly



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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