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Rabbit Anti-VPS41/RBITC Conjugated antibody (bs-12776R-RBITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12776R-RBITC
英文名称1 Rabbit Anti-VPS41/RBITC Conjugated antibody
中文名称 罗丹明(RBITC)标记的液泡蛋白分选蛋白41抗体
别    名 HVPS41; hVps41p; HVSP41; S53; Vacuolar assembly protein 41; Vacuolar protein sorting 41 (yeast homolog); Vacuolar protein sorting 41 (yeast); Vacuolar protein sorting 41 homolog (S. cerevisiae); Vacuolar protein sorting associated protein 41 homolog; vacuolar protein sorting-associated protein 41 homolog; VPS 41.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  转运蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 96kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VPS41
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known. [provided by RefSeq, Jul 2008]

Function:
Required for vacuolar assembly and vacuolar traffic.

Subcellular Location:
Cytoplasmic face of coated pits and vesicles.

Similarity:
Belongs to the VPS41 family.
Contains 1 CHCR (clathrin heavy-chain) repeat.
Contains 1 RING-type zinc finger.

Database links:

Entrez Gene: 420762 Chicken

Entrez Gene: 528654 Cow

Entrez Gene: 27072 Human

Entrez Gene: 218035 Mouse

Entrez Gene: 306991 Rat

Omim: 605485 Human

SwissProt: P49754 Human

SwissProt: Q5KU39 Mouse

Unigene: 592184 Human

Unigene: 27389 Mouse

Unigene: 6409 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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