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Rabbit Anti-p39/CDK5R2/RBITC Conjugated antibody (bs-21065R-RBITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-21065R-RBITC
英文名称1 Rabbit Anti-p39/CDK5R2/RBITC Conjugated antibody
中文名称 罗丹明(RBITC)标记的细胞周期蛋白依赖性激酶5调节亚基2抗体
别    名 CD5R2_HUMAN; CDK5 activator 2; Cdk5r2; Cyclin dependent kinase 5 activator 2; Cyclin dependent kinase 5 regulatory subunit 2; Cyclin-dependent kinase 5 activator 2; Cyclin-dependent kinase 5 regulatory subunit 2; NCK5AI; p39; P39I; p39nck5ai.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  细胞周期蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human p39/CDK5R2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008]

Function:
Activator of CDK5/TPKII.

Subunit:
Heterodimer of a catalytic subunit and a regulatory subunit.

Tissue Specificity:
Brain and neuron specific.

Post-translational modifications:
Myristoylated. The Gly-2-Ala mutant is absent of the cell periphery, suggesting that a proper myristoylation signal is essential for the proper distribution of CDK5R2 (p39).

Similarity:
Belongs to the cyclin-dependent kinase 5 activator family.

Database links:

Entrez Gene: 8941 Human

Entrez Gene: 12570 Mouse

Omim: 603764 Human

SwissProt: Q13319 Human

SwissProt: O35926 Mouse

Unigene: 158460 Human

Unigene: 153833 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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