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Rabbit Anti-USP52/Pan2/PE-Cy7 Conjugated antibody (bs-21012R-PE-Cy7)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-21012R-PE-Cy7
英文名称1 Rabbit Anti-USP52/Pan2/PE-Cy7 Conjugated antibody
中文名称 PE-Cy7标记的泛素特异性蛋白酶52抗体
别    名 hPan2; Inactive ubiquitin carboxyl terminal hydrolase 52; Inactive ubiquitin carboxyl-terminal hydrolase 52; KIAA0710; PAB dependent poly(A) specific ribonuclease subunit 2; PAB-dependent poly(A)-specific ribonuclease subunit 2; PABP dependent poly(A) nuclease 2; PAN 2; PAN2; PAN2 homolog PABP1 dependent poly A specific ribonuclease subunit; PAN2 poly(A) specific ribonuclease subunit homolog; PAN2 polyA specific ribonuclease subunit homolog; PAN2_HUMAN; Ubiquitin specific peptidase 52; Ubiquitin specific protease 52; USP 52; USP52.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  发育生物学  转录调节因子  表观遗传学  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Rabbit, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 135kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human USP52/Pan2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

Function:
Functions in cytoplasmic mRNA decay. As part of the Pan nuclease complex, shortens poly(A) tails of RNA when the poly(A) stretch is bound by polyadenylate-binding protein.

Subcellular Location:
Cytoplasm. Nucleus. Shuttles between nucleus and cytoplasm.

Similarity:
Belongs to the peptidase C19 family.
PAN2 subfamily.
Contains 1 exonuclease domain.

Database links:

Entrez Gene: 9924 Human

Entrez Gene: 103135 Mouse

Entrez Gene: 408200 Rat

SwissProt: Q504Q3 Human

SwissProt: Q8BGF7 Mouse

SwissProt: Q6IE70 Rat

Unigene: 273397 Human

Unigene: 244183 Mouse

Unigene: 9091 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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