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Rabbit Anti-REXO1/Gold Conjugated antibody (bs-19839R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-19839R-Gold
英文名称 Anti-REXO1/Gold
中文名称 胶体金标记的转录延伸因子结合蛋白1抗体
别    名 EloA BP1; ELOABP1; Elongin A binding protein 1; KIAA1138; REX1, RNA exonuclease 1 homolog (S. cerevisiae); RNA exonuclease 1 homolog; TCEB3BP1; Transcription elongation factor B polypeptide 3 binding protein 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 131kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human REXO1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
REXO1 or Elongin A-binding protein 1 (EloA-BP1) is an exonuclease domain-containing protein that can bind to Elongin. The Elongin complex stimulates the rate of transcription elongation by RNA polymerase II by suppressing the transient pausing of the polymerase at many sites along the DNA template. REXO1 is composed of 1221 amino acids and its mRNA is ubiquitously expressed. EloA-BP1 is capable of binding not only the NH(2)-terminal approximately 120 amino acid region of Elongin A, but also that of SII. Although REXO1 had no detectable effect on the rate of transcription elongation in vitro, it may play some role in the regulation of elongation in vivo.

Function:
Seems to have no detectable effect on transcription elongation in vitro.

Subunit:
Interacts with TCEA2 and TCEB3.

Subcellular Location:
Nuclear

Similarity:
Belongs to the REXO1/REXO3 family.
Contains 1 exonuclease domain.

Database links:

Entrez Gene: 57455 Human

Omim: 609614 Human

SwissProt: Q8N1G1 Human

Unigene: 192477 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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