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Rabbit Anti-Relaxin 2/Gold Conjugated antibody (bs-19835R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-19835R-Gold
英文名称 Rabbit Anti-Relaxin 2/Gold Conjugated antibody
中文名称 胶体金标记的松弛肽2/松弛素2抗体
别    名 H2; H2-preprorelaxin; H2-RLX; Prorelaxin H2; REL2_HUMAN; Relaxin 2 (H2); Relaxin 2; Relaxin A chain; Relaxin H2; Relaxin, Ovarian, Of Pregnancy; RLN2; RLXH2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  信号转导  生长因子和激素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Relaxin 2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013]

Function:
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.

Subcellular Location:
Secreted.

Tissue Specificity:
Isoform 1 is expressed in the ovary during pregnancy. Also expressed in placenta, decidua and prostate. Isoform 2 is relatively abundant in placenta. It is in much lower abundance in the prostate gland. Not detected in the ovary.

Similarity:
Belongs to the insulin family.

Database links:

Entrez Gene: 6013 Human

Entrez Gene: 6019 Human

Entrez Gene: 25616 Rat

Omim: 179740 Human

SwissProt: P04090 Human

SwissProt: P04808 Human

SwissProt: P47932 Mouse

SwissProt: P01347 Rat

Unigene: 127032 Human

Unigene: 368996 Human

Unigene: 5033 Mouse

Unigene: 9830 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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