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Rabbit Anti-Secretory phospholipase A2/PE-Cy5.5 Conjugated antibody (bs-20533R-PE-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-20533R-PE-Cy5.5
英文名称1 Rabbit Anti-Secretory phospholipase A2/PE-Cy5.5 Conjugated antibody
中文名称 PE-Cy5.5标记的分泌型磷脂酶A2抗体
别    名 C 3.1.1.4; GIIC sPLA2; Group IIA phospholipase A2; membrane associated; Modifier of MIN 1 mouse homolog; MOM1; Non-pancreatic secretory phospholipase A2; NPS PLA2; NPS-PLA2; PA2GA_HUMAN; Phosphatidylcholine 2-acylhydrolase 2A; Phosphatidylcholine 2acylhydrolase; Phospholipase A2; Phospholipase A2 group IIA (platelets, synovial fluid); Phospholipase A2 membrane associated; Phospholipase A2 polypeptide B; Phospholipase A2 synovial; PLA2; PLA2B; PLA2G2A; PLA2L; PLA2S; PLAS1; RASF A; sPLA2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Secretory phospholipase A2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]

Function:
Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.

Subcellular Location:
Membrane.

Similarity:
Belongs to the phospholipase A2 family.

Database links:

Entrez Gene: 5320 Human

Entrez Gene: 18780 Mouse

Entrez Gene: 29692 Rat

Omim: 172411 Human

SwissProt: P14555 Human

SwissProt: P31482 Mouse

SwissProt: P14423 Rat

Unigene: 466804 Human

Unigene: 4675 Mouse

Unigene: 11346 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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