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Rabbit Anti-LRTOMT/LRRC51/Cy5.5 Conjugated antibody (bs-18423R-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-18423R-Cy5.5
英文名称 Rabbit Anti-LRTOMT/LRRC51/Cy5.5 Conjugated antibody
中文名称 Cy5.5标记的富含亮氨酸重复蛋白51抗体
别    名 COMT2; DFNB63; Leucine rich repeat-containing protein 51; Leucine rich transmembrane and 0-methyltransferase domain containing; LRRC51; LRTOMT1; LRTOMT2; Protein LRTOMT1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  神经生物学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, hu, mo, rat, dog)
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LRTOMT/LRRC51
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR)-containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs; the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene. [provided by RefSeq, Sep 2012]

Subcellular Location:
Cytoplasmic

Similarity:
Contains 3 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.

Database links:

Entrez Gene: 220074 Human

Entrez Gene: 69358 Mouse

Omim: 612414 Human

SwissProt: Q96E66 Human

SwissProt: Q9DAK8 Mouse

SwissProt: B6CZ61 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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