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Rabbit Anti-zcrb1/BF647 Conjugated antibody (bs-18567R-BF647)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-18567R-BF647
英文名称 Rabbit Anti-zcrb1/BF647 Conjugated antibody
中文名称 BF647标记的zcrb1蛋白抗体
别    名 MADP 1; MADP1; RBM36; SNRNP31; U11/U12 small nuclear ribonucleoprotein 31 kDa protein; U11/U12 snRNP 31 kDa protein; U11/U12 snRNP 31K; U11/U12-31K; ZCCHC19; Zcrb1; ZCRB1_HUMAN; zinc finger CCHC-type and RNA binding motif 1; Zinc finger CCHC-type and RNA-binding motif-containing protein 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  锌指蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human zcrb1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. [provided by RefSeq, Jul 2008]

Subunit:
Component of the U11/U12 snRNPs that are part of the U12-type spliceosome.

Subcellular Location:
Nucleus

Similarity:
Contains 1 CCHC-type zinc finger.
Contains 1 RRM (RNA recognition motif) domain.

Database links:

Entrez Gene: 85437 Human

Entrez Gene: 67197 Mouse

Entrez Gene: 362990 Rat

Omim: 610750 Human

SwissProt: Q8TBF4 Human

SwissProt: Q9CZ96 Mouse

SwissProt: Q499V6 Rat

Unigene: 496279 Human

Unigene: 293181 Mouse

Unigene: 136969 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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