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Rabbit Anti-KIF15/AP Conjugated antibody (bs-10693R-AP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-10693R-AP
英文名称 Anti-KIF15/AP
中文名称 碱性磷酸酶(AP)标记的驱动蛋白家族成员15抗体
别    名 Kinesin like protein 7; KLP2; FLJ25667; HKLP2; Kinesin family member 15; Kinesin like protein 2; Kinesin like protein 7; Kinesin like protein KIF15; KLP2; KNSL7; Linesin like 7; NY BR 62; NYBR62; Serologically defined breast cancer antigen NY BR 62; Serologically defined breast cancer antigen NYBR62; FLJ25667; KIF15_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  细胞骨架  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Horse, )
产品应用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 160kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KIF15
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
KIF15 belongs to the kinesin-like protein family and contains 1 kinesin-motor domain. KIF15 is the plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly.

Function:
Plus-end directed kinesin-like motor enzyme involved inmitotic spindle assembly.

Subunit:
Interacts with MKI67 and TPX2.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton, spindle.Note=Detected during the interphase in the cytoplasm as finelypunctuate pattern and irregularly shaped dots. Detected duringmitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis.Localizes at the central spindle at anaphase.Localizes at the sites of invaginating cell membranes, a positionthat corresponds to the location of the contractile actomyosin ringof dividing cells. Colocalizes with actin ininterphase. Colocalizes in dendrites and in growthcone of axons with microtubules.

Tissue Specificity:
Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis.

Similarity:
Belongs to the kinesin-like protein family. KLP2subfamily.
Contains 1 kinesin-motor domain.

Database links:

Entrez Gene: 56992 Human

Entrez Gene: 209737 Mouse

Entrez Gene: 353302 Rat

SwissProt: Q9NS87 Human

SwissProt: Q6P9L6 Mouse

SwissProt: Q7TSP2 Rat

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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