| 产品编号 | bs-18364R-AF488 |
| 英文名称 | Anti-LRP3/AF488 |
| 中文名称 | AF488标记的低密度脂蛋白受体相关蛋白3抗体 |
| 别 名 | 105 kDa low-density lipoprotein receptor-related protein; hLRp105; Low density lipoprotein receptor related protein 3; Low-density lipoprotein receptor-related protein 3; LRP-3; Lrp3; LRP3_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 细胞膜受体 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, ) |
| 产品应用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 79kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LRP3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: Low-density lipoprotein receptor-related protein 3 (LRP3) is a 770 amino acid protein that contains two CUB domains and four LDL-receptor class A domains. LRP3 is widely expressed with highest expression in skeletal muscle and ovary and lowest expression in testis, colon and leukocytes. LRP3 is potentially a membrane receptor involved in the internalization of lipophilic molecules and/or signal transduction. Function: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro. Subcellular Location: Membrane. Membrane > coated pit.Target information above from: UniProt accession O75074 The UniProt Consortium The Universal Protein Resource (UniProt) in 2010 Nucleic Acids Res. 38:D142-D148 (2010) . Tissue Specificity: Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte. Similarity: Belongs to the LDLR family. Contains 2 CUB domains. Contains 4 LDL-receptor class A domains. Database links: Entrez Gene: 4037 Human Entrez Gene: 435965 Mouse Omim: 603159 Human SwissProt: O75074 Human Unigene: 515340 Human Unigene: 273631 Mouse Unigene: 145216 Rat Unigene: 87059 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
