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Rabbit Anti-LETM2/Gold Conjugated antibody (bs-18225R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-18225R-Gold
英文名称1 Rabbit Anti-LETM2/Gold Conjugated antibody
中文名称 胶体金标记的线粒体LETM2抗体
别    名 LETM1 and EF hand domain containing protein 2; LETM1 and EF-hand domain-containing protein 2; LETM1 domain containing protein LETM2 mitochondrial; LETM1 domain-containing protein LETM2; Letm2; LETM2_HUMAN; Leucine zipper EF hand containing transmembrane protein 1 like; Leucine zipper EF hand containing transmembrane protein 2; Leucine zipper-EF-hand-containing transmembrane protein 1-like; mitochondrial.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  免疫学  线粒体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LETM2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
LETM2 is a 491 amino acid protein that is localized to the mitochondrial membrane and contains one LETM1 domain. Despite its name, LETM2, which is preferentially expressed in sperm and testis, does not contain any EF-hand domains. There are four isoforms of LETM2 that are produced as a result of alternative splicing events. A homolog of LETM2, LETM1 is thought to be involved in maintaining normal mitochondrial function and overall cell viability. Deletions in the gene encoding LETM1 are associated with Wolf-Hirschhorn syndrome (WHS), a congenital syndrome characterized by a number of abnormalities, including mental retardation, seizures, heart defects, fused teeth, hearing loss, a webbed neck and renal abnormalities. The LETM2 gene is located on chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes.

Subcellular Location:
Mitochondrion inner membrane.

Similarity:
Contains 1 LETM1 domain.

Database links:

Entrez Gene: 137994 Human

GenBank: NP_653253.1 Human

SwissProt: Q2VYF4 Human

Unigene: 696457 Human

Unigene: 734005 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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