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Rabbit Anti-LCMT2/AP Conjugated antibody (bs-18191R-AP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-18191R-AP
英文名称 Rabbit Anti-LCMT2/AP Conjugated antibody
中文名称 碱性磷酸酶(AP)标记的LCMT2蛋白抗体
别    名 KIAA0547; LCMT 2; Lcmt2; LCMT2_HUMAN; Leucine carboxyl methyltransferase 2; MGC9534; p21WAF1/CIP1 promoter interacting protein; p21WAF1/CIP1 promoter-interacting protein; PPM2; tRNA Wybutosine synthesizing protein 4; tRNA wybutosine synthesizing protein 4 homolog; tRNA wybutosine-synthesizing protein 4 homolog; tRNA yW synthesizing protein 4; tRNA yW synthesizing protein 4 homolog; tRNA yW-synthesizing protein 4 homolog; TYW4.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Cow, )
产品应用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 76kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LCMT2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW). [provided by RefSeq, Jul 2008]

Function:
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues.

Similarity:
Belongs to the methyltransferase superfamily. LCMT family.

Database links:

Entrez Gene: 9836 Human

Entrez Gene: 296098 Rat

Omim: 611246 Human

SwissProt: O60294 Human

SwissProt: Q5XIA3 Rat

Unigene: 200596 Human

Unigene: 533913 Human

Unigene: 741946 Human

Unigene: 17983 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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