| 产品编号 | bs-17747R-AP |
| 英文名称 | Rabbit Anti-MR1/AP Conjugated antibody |
| 中文名称 | 碱性磷酸酶（AP）标记的组织相容性复合物相关蛋白MR1抗体 |
| 别 名 | Class I histocompatibility antigen like protein; HLALS; Major histocompatibility complex class I like sequence; Major histocompatibility complex class I related; Major histocompatibility complex class I related gene protein; Major histocompatibility complex class I related isoform CRA a; Major histocompatibility complex class I related isoform CRA c; Major histocompatibility complex class I related isoform CRA d; MHC class I like antigen MR 1; MHC class I like antigen MR1; MHC class I related gene protein; MHC class I related protein 1 isoform B; MHC class I related protein 1 isoform C; MR 1; Mr1 protein; MR1B; MR1C. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, (predicted: Human, Rat, ) |
| 产品应用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 39kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MR1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: MR1 is a 341 amino acid single-pass membrane protein that localizes to the endoplasmic reticulum, as well as to the extracellular side of the cell membrane, and contains one Ig-like C1-type domain. Expressed ubiquitously, MR1 exists as a heterodimer with β-2-Microglobulin and plays an important role in antigen presentation, specifically in the development and expansion of mucosal-associated invariant T cells (MAITs). MAITs are located in the gut and are involved in monitoring flora levels, as well as in conveying distress signals to other areas of the body, indicating a role for MR1 in proper digestion and immune system function. MR1 exists as four alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 1. Function: Similar to a typical class I MHC molecule, the MR1 (MHC-related 1) protein comprises a signal sequence, 3 extracellular domains (alpha-1, alpha-2, and alpha-3), a transmembrane domain, and a cytoplasmic domain. MR1 encodes peptide-binding domains similar to those encoded by HLA class I genes. Database links: Entrez Gene: 3140 Human Omim: 600764 Human SwissProt: Q95460 Human Unigene: 101840 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
