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Rabbit Anti-MOXD1/PE-Cy5.5 Conjugated antibody (bs-17733R-PE-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-17733R-PE-Cy5.5
英文名称 Rabbit Anti-MOXD1/PE-Cy5.5 Conjugated antibody
中文名称 PE-Cy5.5标记的单加氧酶X抗体
别    名 DBH like monooxygenase protein 1; DBH-like monooxygenase protein 1; dJ248E1.1; DKFZp564G202; Monooxygenase X; monooxygenase, DBH like 1; MOX; Moxd1; MOXD1_HUMAN; PRO5780.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  细胞类型标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 68kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MOXD1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
MOXD1 is a 613 amino acid single-pass type I membrane protein of the Endoplasmic reticulum that belongs to the copper type II ascorbate-dependent monooxygenase family. Existing as two alternatively spliced isoforms, MOXD1 is expressed in adult spinal cord, adrenal gland, brain, testis, uterus, lung and kidney, as well as fetal liver and brain. MOXD1 is upregulated during replicative senescence in primary fibroblast and umbilical vein endothelial cell cultures, and uses two copper ions per subunit as a cofactor. MOXD1 contains one DOMON domain, undergoes post-translational N-glycosylation and is encoded by a gene that maps to human chromosome 6. Chromosome 6 contains 170 million base pairs, comprises nearly 6% of the human genome and is associated with early onset intestinal cancer, Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in lung, kidney, brain and spinal cord.

Post-translational modifications:
N-glycosylated.

Similarity:
Belongs to the copper type II ascorbate-dependent monooxygenase family. Contains 1 DOMON domain.

Database links:

Entrez Gene: 26002 Human

Entrez Gene: 59012 Mouse

Entrez Gene: 294119 Rat

Omim: 609000 Human

SwissProt: Q6UVY6 Human

SwissProt: Q9CXI3 Mouse

Unigene: 6909 Human

Unigene: 285934 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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