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Rabbit Anti-MOGAT2/Biotin Conjugated antibody (bs-17705R-Bio)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-17705R-Bio
英文名称 Anti-MOGAT2/Biotin
中文名称 生物素标记的MOGAT2蛋白抗体
别    名 2 acylglycerol O acyltransferase 2; 2-acylglycerol O-acyltransferase 2; Acyl CoA:monoacylglycerol acyltransferase 2; Acyl-CoA:monoacylglycerol acyltransferase 2; DC5; DGAT2L5; Diacylglycerol acyltransferase 2 like protein 5; Diacylglycerol acyltransferase 2-like protein 5; Diacylglycerol O acyltransferase candidate 5; Diacylglycerol O-acyltransferase candidate 5; EC 2.3.1.22; FLJ22644; hDC5; hMGAT2; Mgat1l; MGAT2; MGC119183; MGC119184; MGC119185; MGC189143; mogat2; MOGT2_HUMAN; Monoacylglycerol O acyltransferase 1 like; Monoacylglycerol O acyltransferase 2; Monoacylglycerol O-acyltransferase 2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, )
产品应用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MOGAT2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Dietary fat absorption from the small intestine is facilitated by acyl-CoA:monoacylglycerol transferase (MOGAT; EC 2.3.1.22) and acyl-CoA:diacylglycerol acyltransferase (DGAT; see MIM 604900) activities. MOGAT catalyzes the joining of monoacylglycerol and fatty acyl-CoAs to form diacylglycerol (Yen and Farese, 2003 [PubMed 12621063]).[supplied by OMIM, Mar 2008]

Function:
Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in liver, small intestine, colon, stomach and kidney.

Similarity:
Belongs to the diacylglycerol acyltransferase family.

Database links:

Entrez Gene: 80168 Human

Entrez Gene: 233549 Mouse

Entrez Gene: 681211 Rat

Omim: 610270 Human

SwissProt: Q3SYC2 Human

SwissProt: Q80W94 Mouse

Unigene: 288568 Human

Unigene: 208030 Mouse

Unigene: 19175 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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