| 产品编号 | bs-18021R-AF594 |
| 英文名称 | Anti-ORAI3/AF594 |
| 中文名称 | AF594标记的嗅觉受体AI3抗体 |
| 别 名 | MGC13024; Orai 3; ORAI calcium release activated calcium modulator 3; Orai3; ORAI3_HUMAN; Protein orai 3; Protein orai-3; TMEM 142C; TMEM142C; Transmembrane protein 142C. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, ) |
| 产品应用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ORAI3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: Orai3 (ORAI calcium release-activated calcium modulator 3), also known as TMEM142C (transmembrane protein 142C), is a 295 amino acid multi-pass membrane protein that belongs to the Orai family of proteins. Localizing to the plasma membrane, Orai3 plays an important role in store-operated calcium (SOC) entry, a process involving Ca(2+) influx and replenishment of Ca(2+) stores formerly emptied through the action of inositol 1,4,5-trisphosphate production and other Ca(2+) mobilizing agents. CRAC channels are responsible for mediating calcium influx in T cells and play an important role in the immune response. Orai3, specifically, also acts as a regulator or component of the nuclear import of transcription factor NFAT. Function: Key regulator or component of store-operated Ca(2+) channel and transcription factor NFAT nuclear import. Subunit: Interacts with CRACR2A/EFCAB4B. Subcellular Location: Membrane. Similarity: Belongs to the Orai family. Database links: Entrez Gene: 93129 Human Entrez Gene: 269999 Mouse Omim: 610930 Human SwissProt: Q9BRQ5 Human SwissProt: Q6P8G8 Mouse Unigene: 729239 Human Unigene: 36852 Mouse Unigene: 42186 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
