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Rabbit Anti-SIDT2/Cy5 Conjugated antibody (bs-17485R-Cy5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-17485R-Cy5
英文名称1 Rabbit Anti-SIDT2/Cy5 Conjugated antibody
中文名称 Cy5标记的SIDT2蛋白抗体
别    名 SIDT-2; B930096O19; BC023957; CGI 40; DKFZp686L17253; FLJ90656; MGC36407; MGC58967; RGD1308311; SID1 transmembrane family member 2; SID1 transmembrane family, member 2; SIDT2; SIDT2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  通道蛋白  跨膜蛋白  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 93kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SIDT2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
SID-1 and SID-2 belong to the systemic RNA interference defective-1 (SID1) family of transmembrane proteins. SID-1, originally identified in C. elegans, is an 827 amino acid long protein. It localizes to the cell membrane and contains eleven transmembrane domains. This suggests that SID-1 possibly functions as a channel protein. The overexpression of SID-1 enhances double stranded RNA (dsRNA) uptake in pancreatic ductal adenocarcinoma cells. SID-2, also first identified in C. elegans, is an 832 amino acid long protein with multiple transmembrane domains. At least two isoforms exist for SID-2 due to alternative splicing. Isoform 2 contains an additional 21 amino acids after residue 387 and has an alternate sequence that is 8 amino acids shorter for residues 814 to 832 of isoform 1.

Subcellular Location:
Lysosome membrane.

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the SID1 family.

Database links:

Entrez Gene: 51092 Human

Entrez Gene: 214597 Mouse

Entrez Gene: 315617 Rat

SwissProt: Q8NBJ9 Human

SwissProt: Q8CIF6 Mouse

SwissProt: D3ZEH5 Rat

Unigene: 712144 Human

Unigene: 379345 Mouse

Unigene: 162997 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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