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Rabbit Anti-Defensin alpha 5/PE-Cy3 Conjugated antibody (bs-10577R-PE-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-10577R-PE-Cy3
英文名称 Rabbit Anti-Defensin alpha 5/PE-Cy3 Conjugated antibody
中文名称 PE-Cy3标记的防御素α5抗体
别    名 alpha 5; alpha 5 Defensin; DEF5; DEF5_HUMAN; DEF5_RAT; Defa; Defa29; DEFA5; Defcr29; Defcr5; Defensin 5; Defensin alpha-5; Defensin alpha 5 Paneth cell specific; Defensin alpha 5 preproprotein; Defensin; Enteric defensin; HD 5; HD5; HD5(20-94); HD5(63-94); MGC129728; RD 5.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Rat, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 4.1kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Defensin alpha 5
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.

Function:
Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.

Subcellular Location:
Secreted. Cytoplasmic vesicle, secretory vesicle. Peptides HD5(20-94), HD5(23-94) and HD5(29-94) are found within tissues, HD5(20-94) being the predominant intracellular form. Peptides HD5(56-94) and HD5(63-94) are found in the extracellular milieu, HD5(63-94) being the most abundant form.

Tissue Specificity:
Paneth cells of the small intestine (at protein level).

Post-translational modifications:
Glycosylated.

Similarity:
Belongs to the alpha-defensin family.

Database links:

Entrez Gene: 1670 Human

Omim: 600472 Human

SwissProt: Q01523 Human

Unigene: 655233 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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