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Rabbit Anti-OSCAR/HRP Conjugated antibody (bs-17523R-HRP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-17523R-HRP
英文名称1 Rabbit Anti-OSCAR/HRP Conjugated antibody
中文名称 辣根过氧化物酶标记的破骨细胞相关受体抗体
别    名 hOSCAR; hOSCARM2; hOSCARM3; mOSCAR; Oscar; Oscar protein; OSCAR_HUMAN; OSCARS1; OSCARS2; Osteoclast associated immunoglobulin like receptor; Osteoclast associated receptor; Osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; PIgR-3; PIGR3; Poly Ig receptor 3; Poly-Ig receptor 3; Polymeric immunoglobulin receptor 3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  细胞类型标志物  t-淋巴细胞  b-淋巴细胞  细胞骨架  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, )
产品应用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human OSCAR
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

Function:
Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.

Subcellular Location:
Secreted and Cell membrane.

Similarity:
Belongs to the leukocyte receptor complex/polymeric immunogobulin receptor (PIR/LRC) family.
Contains 2 Ig-like (immunoglobulin-like) domains.

Database links:

Entrez Gene: 126014 Human

Omim: 606862 Human

SwissProt: Q8IYS5 Human

Unigene: 347655 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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