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Rabbit Anti-KIF22/Gold Conjugated antibody (bs-17049R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-17049R-Gold
英文名称 Rabbit Anti-KIF22/Gold Conjugated antibody
中文名称 胶体金标记的驱动蛋白家族成员22抗体
别    名 A 328A3.2; KID; KIF 22; kif22; KIF22_HUMAN; Kinesin family member 22; Kinesin like 4; Kinesin like DNA binding protein; Kinesin like DNA binding protein pseudogene; Kinesin like protein 4; Kinesin like protein KIF22; Kinesin-like DNA-binding protein; Kinesin-like protein 4; Kinesin-like protein KIF22; KNSL 4; KNSL4; OBP 1; OBP 2; OBP; OBP1; OBP2; Origin of plasmid DNA replication binding protein; OriP binding protein; OTTHUMP00000123406.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Zebrafish, Sheep, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 73kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KIF22
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Function:
Kinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA.

Subcellular Location:
Nucleus. Cytoplasm; cytoskeleton.

Post-translational modifications:
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.

Similarity:
Belongs to the kinesin-like protein family.
Contains 1 kinesin-motor domain.

Database links:

Entrez Gene: 3835 Human

Entrez Gene: 110033 Mouse

Entrez Gene: 293502 Rat

Omim: 603213 Human

SwissProt: Q14807 Human

SwissProt: Q3V300 Mouse

SwissProt: Q5I0E8 Rat

Unigene: 612151 Human

Unigene: 286488 Mouse

Unigene: 8601 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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