| 产品编号 | bs-17359R-BF647 |
| 英文名称 | Rabbit Anti-HCFC1R1/BF647 Conjugated antibody |
| 中文名称 | BF647标记的宿主细胞因子C1调节蛋白1抗体 |
| 别 名 | HCF 1 beta propeller interacting protein; HCF-1 beta-propeller-interacting protein; HCF1 beta propeller interacting protein; HCFC1R1; Host cell factor C1 regulator 1 (XPO1 dependent); Host cell factor C1 regulator 1; HPIP; HPIP_HUMAN; Inhibitor of four 2. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 信号转导 生长因子和激素 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Mouse, Rat, (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 产品应用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 15kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HCFC1R1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background: PSTPIP1 is a 416 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one SH3 domain and one FCH domain. Expressed at high levels in T cells and spleen and present at lower levels in thymus, lung, placenta and small intestine, PSTPIP1 interacts with CD2AP, BDP1 and c-Abl and is involved in the regulation of the Actin cytoskeleton, possibly functioning as a scaffold protein that may promote Actin polymerization. Defects in the gene encoding PSTPIP1 are the cause of PAPA syndrome (PAPAS), an autosomal dominant disease characterized by recurring inflammatory episodes that affect skin and joint tissue. Multiple isoforms of PSTPIP1 exist due to alternative splicing events. Function: Regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus. Subcellular Location: Cytoplasm. Nucleus. Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner. Tissue Specificity: Widely expressed. Database links: Entrez Gene: 54985 Human Entrez Gene: 353502 Mouse SwissProt: Q9NWW0 Human SwissProt: Q9CYQ5 Mouse Unigene: 423103 Human Unigene: 728247 Human Unigene: 359030 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 1、抗体溶解方法 | |
| 2、抗体修复方式 | |
| 3、常用试剂的配制 | |
| 4、免疫组化操作步骤 | |
| 5、免疫组化问题解答 | |
| 6、Western Blotting 操作步骤 | |
| 7、Western Blotting 问题解答 | |
| 8、关于肽链的设计 | |
| 9、多肽的溶解与保存 | |
| 10、酶标抗体效价测定程序 | |
