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Rabbit Anti-SFXN1/PE-Cy3 Conjugated antibody (bs-17306R-PE-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-17306R-PE-Cy3
英文名称1 Rabbit Anti-SFXN1/PE-Cy3 Conjugated antibody
中文名称 PE-Cy3标记的三羧酸载体蛋白SFXN1抗体
别    名 FLJ12876; SFXN1; SFXN1_HUMAN; Sideroflexin 1; Sideroflexin-1; TCC; Tricarboxylate carrier protein.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  神经生物学  信号转导  新陈代谢  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SFXN1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The sideroflexin (SFXN) family is comprised of SFXN1, SFXN2, SFXN3, SFXN4 and SFXN5. SFXN1, also designated tricarboxylate carrier protein TCC, is the most highly characterized family member. The ubiquitously expressed SFXN1 protein resides as an integral protein of the mitochondrial inner membrane. It functions as an essential component of the shuttle system that transports mitochondrial acetyl-CoA into the cytosol, where lipogenesis occurs. The SFXN1 gene is mutated in flexed-tail (f/f) mice, which display axial skeletal abnormalities and a transient embryonic and neonatal anemia characterized by pathologic intramitochondiral iron deposits in erythrocytes. Therefore, SFXN1 is also thought to facilitate the transport of a component required for iron utilization into mitochondria. All SFXN family members show expression in pancreatic islet cells. SFXN5 displays a citrate transport activity and is primarily expressed in brain.

Function:
Might be involved in the transport of a component required for iron utilization into or out of the mitochondria.

Subcellular Location:
Mitochondrion membrane.

Similarity:
Belongs to the sideroflexin family.

Database links:

Entrez Gene: 94081 Human

Entrez Gene: 14057 Mouse

Entrez Gene: 364678 Rat

GenBank: NM_022754 Human

SwissProt: Q9H9B4 Human

SwissProt: Q99JR1 Mouse

SwissProt: Q63965 Rat

Unigene: 369440 Human

Unigene: 134191 Mouse

Unigene: 115752 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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