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Rabbit Anti-GABARAPL3/PE-Cy7 Conjugated antibody (bs-16204R-PE-Cy7)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16204R-PE-Cy7
英文名称 Rabbit Anti-GABARAPL3/PE-Cy7 Conjugated antibody
中文名称 PE-Cy7标记的γ氨基丁酸受体相关蛋白样3抗体
别    名 ATG8D; GABA(A) receptor associated protein like 3; GABA(A) receptors associated protein like 3 pseudogene; GABARAPL3; Gamma-aminobutyric acid receptor associated protein-like 3; GBRL3_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GABARAPL3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 Function:
Ubiquitin-like modifier involved in autophagosome formation. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity).

Subunit:
Interacts with GABRG2 and beta-tubulin (By similarity).

Subcellular Location:
Cytoplasmic; cytoskeleton (Probable). Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor (Probable).

Tissue Specificity:
Ubiquitous. Expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta and skeletal muscle. Expressed at very low levels in thymus and small intestine.

Post-translational modifications:
The precursor molecule is cleaved by ATG4B to form the cytosolic form, GABARAPL3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, GABARAPL3-II. ATG4B also mediates the delipidation required for GABARAPL1 recycling when autophagosomes fuse with lysosomes (By similarity).

Similarity:
Belongs to the ATG8 family.

Database links:

Entrez Gene: 23766 Human

SwissProt: Q9BY60 Human

Unigene: 592014 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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