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Rabbit Anti-KCTD3/FITC Conjugated antibody (bs-16934R-FITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16934R-FITC
英文名称1 Rabbit Anti-KCTD3/FITC Conjugated antibody
中文名称 FITC标记的肾细胞癌抗原NYREN 45抗体
别    名 BTB/POZ domain-containing protein KCTD3; Kctd3; KCTD3_HUMAN; MGC43935; NY REN 45; NY REN 45 antigen; NY REN45; NYREN 45; OTTHUMP00000035070; Potassium channel tetramerisation domain containing 3; Renal carcinoma antigen NY REN 45; Renal carcinoma antigen NY-REN-45.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  免疫学  神经生物学  肿瘤细胞生物标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Horse, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 89kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCTD3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Tissue Specificity:
Broadly expressed in normal tissues.

Similarity:
Belongs to the KCTD3 family.
Contains 1 BTB (POZ) domain.
Contains 5 WD repeats.

Database links:

Entrez Gene: 51133 Human

Entrez Gene: 226823 Mouse

Entrez Gene: 305055 Rat

Omim: 613272 Human

SwissProt: Q9Y597 Human

SwissProt: Q8BFX3 Mouse

Unigene: 335139 Human

Unigene: 209880 Mouse

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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