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Rabbit Anti-KAP3.3/Cy3 Conjugated antibody (bs-16851R-Cy3)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16851R-Cy3
英文名称 Rabbit Anti-KAP3.3/Cy3 Conjugated antibody
中文名称 Cy3标记的角蛋白相关蛋白KAP3.3抗体
别    名 KRTAP3-3 High sulfur keratin-associated protein 3.3; KAP3.3; Keratin-associated protein 3-3; Keratin-associated protein 3.3; KRA33_HUMAN; Krtap3-3; KRTAP3.3.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Cow, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KAP3.3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008]

Function:
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

Tissue Specificity:
Localized to the upper cortex of the hair shaft.

Similarity:
Belongs to the KRTAP type 3 family.

Database links:

Entrez Gene: 768045 Cow

Entrez Gene: 85293 Human

Entrez Gene: 66380 Mouse

Entrez Gene: 363678 Rat

SwissProt: Q24JX9 Cow

SwissProt: Q9BYR6 Human

SwissProt: Q9D7P0 Mouse

Unigene: 662759 Human

Unigene: 30539 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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