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Rabbit Anti-LACTB/BF488 Conjugated antibody (bs-16882R-BF488)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16882R-BF488
英文名称1 Rabbit Anti-LACTB/BF488 Conjugated antibody
中文名称 BF488标记的β内酰胺酶样蛋白抗体
别    名 FLJ14902; G24; Lactamase, beta; LACTB; Mitochondrial 39S ribosomal protein L56; mitochondrial ribosomal protein L56; MRPL56; LACTB_HUMAN; Serine beta lactamase like protein LACTB; serine beta-lactamase-like protein LACTB, mitochondria; UNQ843/PRO1781.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  信号转导  转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LACTB
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a mitochondrially-localized protein that has sequence similarity to prokaryotic beta-lactamases. Many of the residues responsible for beta-lactamase activity are not conserved in this protein, suggesting it may have a different enzymatic function. Increased expression of the related mouse gene was found to be associated with obesity. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Dec 2013]

Function:
LACTB is a protein from the large 39S subunit of the mitochondrial ribosome (mitoribosome). It has some sequence similarity to prokaryotic beta-lactamases but most of the residues that are responsible for the beta-lactamase activity are not conserved between the two proteins. It is expressed predominantly in skeletal muscle. There are two named isoforms.

Subcellular Location:
Mitochondrion

Similarity:
Belongs to the peptidase S12 family.

Database links:

Entrez Gene: 114294 Human

Entrez Gene: 80907 Mouse

Entrez Gene: 300803 Rat

Omim: 608440 Human

SwissProt: P83111 Human

SwissProt: Q9EP89 Mouse

Unigene: 410388 Human

Unigene: 157882 Mouse

Unigene: 73451 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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