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Rabbit Anti-KRT23/Gold Conjugated antibody (bs-16818R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-16818R-Gold
英文名称 Rabbit Anti-KRT23/Gold Conjugated antibody
中文名称 胶体金标记的细胞角蛋白23抗体
别    名 CK 23; CK-23; CK23; Cytokeratin 23; Cytokeratin-23; Cytokeratin23; DKFZP434G032; HAIK 1; HAIK1; Histone deacetylase inducible keratin 23; Hyperacetylation inducible type I keratin; K1C23_HUMAN; K23; Keratin 23 (histone deacetylase inducible); Keratin 23; Keratin; Keratin type I cytoskeletal 23; Keratin-23; Keratin23; KRT 23; KRT23; MGC26158; type I cytoskeletal 23; Type I intermediate filament cytokeratin.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KRT23
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Function:
Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. Forms a ternary complex with Dkk1 and LRP6 and induces rapid endocytosis and removal of the Wnt receptor LRP6 from the plasma membrane (By similarity).

Subunit:
Interacts with ERLEC1 (By similarity).

Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential).

Similarity:
Contains 1 CUB domain.
Contains 1 kringle domain.
Contains 1 WSC domain.

Database links:

Entrez Gene: 25984 Human

Omim: 606194 Human

SwissProt: Q9C075 Human

Unigene: 9029 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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