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Rabbit Anti-KREMEN1/Gold Conjugated antibody (bs-16812R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-16812R-Gold
英文名称 Rabbit Anti-KREMEN1/Gold Conjugated antibody
中文名称 胶体金标记的KREMEN1蛋白抗体
别    名 AV002070; Dickkopf receptor; KREM1_HUMAN; KREMEN; Kremen protein 1; Kremen protein 1 precursor; Kremen1; Kringle coding gene marking the eye and the nose; Kringle containing protein marking the eye and the nose; Kringle containing transmembrane protein 1; Kringle containing transmembrane protein; Kringle domain containing transmembrane protein 1; Kringle domain-containing transmembrane protein 1; Kringle-containing protein marking the eye and the nose; KRM1; RP23 293J16.1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  信号转导  细胞膜受体  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse,  (predicted: Human, Rat, Cow, Sheep, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KREMEN1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]

Function:
Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity). {ECO:0000250}.

Subcellular Location:
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Similarity:
Contains 1 CUB domain.

Database links:

Entrez Gene: 83999 Human

Omim: 609898 Human

SwissProt: Q96MU8 Human

Unigene: 229335 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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