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Rabbit Anti-FXL19/Gold Conjugated antibody (bs-16201R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-16201R-Gold
英文名称 Rabbit Anti-FXL19/Gold Conjugated antibody
中文名称 胶体金标记的FXL19蛋白抗体
别    名 F-box and leucine-rich repeat protein 19; F-box/LRR-repeat protein 19; FBL19; Fbxl19; FXL19_HUMAN; JHDM1C; Jumonji C domain containing histone demethylase 1C.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  跨膜蛋白  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 76kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FXL19
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 background:
This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Subunit:
Directly interacts with SKP1 and CUL1 (By similarity).

Similarity:
Contains 1 CXXC-type zinc finger.
Contains 1 F-box domain.
Contains 6 LRR (leucine-rich) repeats.
Contains 1 PHD-type zinc finger.

Database links:

Entrez Gene: 54620 Human

Entrez Gene: 233902 Mouse

Entrez Gene: 308999 Rat

GenBank: BC059173 Human

Omim: 609085 Human

SwissProt: Q6PCT2 Human

SwissProt: Q6PB97 Mouse

Unigene: 152149 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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