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Rabbit Anti-Integrin beta 8/RBITC Conjugated antibody (bs-16615R-RBITC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16615R-RBITC
英文名称 Rabbit Anti-Integrin beta 8/RBITC Conjugated antibody
中文名称 罗丹明(RBITC)标记的整合素β8抗体
别    名 Integrin beta-8; ITB8_HUMAN; ITGB 8; ITGB8.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Pig, Rabbit, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 81kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Integrin beta 8
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Function:
Integrin alpha-V/beta-8 is a receptor for fibronectin.

Subcellular Location:
Membrane.

Tissue Specificity:
Placenta, kidney, brain, ovary, uterus and in several transformed cells. Transiently expressed in 293 human embryonic kidney cells.

Similarity:
Belongs to the integrin beta chain family.
Contains 1 VWFA domain.

Database links:

Entrez Gene: 3696 Human

Entrez Gene: 536286 Cow

Entrez Gene: 475253 Dog

Entrez Gene: 320910 Mouse

Entrez Gene: 100037284 Pig

Entrez Gene: 100009141 Rabbit

Entrez Gene: 362800 Rat

Omim: 604160 Human

SwissProt: P26012 Human

SwissProt: P26013 Rabbit

Unigene: 592171 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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