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Rabbit Anti-HSD17B7/APC Conjugated antibody (bs-16528R-APC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-16528R-APC
英文名称1 Rabbit Anti-HSD17B7/APC Conjugated antibody
中文名称 APC标记的17β羟类固醇脱氢酶7抗体
别    名 17 beta HSD 7; 17 beta hydroxysteroid dehydrogenase 7; 17 beta hydroxysteroid dehydrogenase type VII; 17-beta-HSD 7; 17-beta-hydroxysteroid dehydrogenase 7; 17beta hydroxysteroid dehydrogenase; 3 keto steroid reductase; 3-keto-steroid reductase; DHB7_HUMAN; Estradiol 17 beta dehydrogenase 7; Estradiol 17-beta-dehydrogenase 7; Hsd17b7; hydroxysteroid (17 beta) dehydrogenase 7; MGC12523; MGC75018; PRAP; SDR37C1; Short chain dehydrogenase/reductase family 37C member 1.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  新陈代谢  细胞膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HSD17B7
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).[supplied by OMIM, May 2010]

Function:
Responsible for the reduction of the keto group on the C-3 of sterols.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. Isoform 3 is expressed in eye ciliary epithelial cells and neuroendocrine cells.

Post-translational modifications:
Phosphorylated.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

Database links:

Entrez Gene: 51478 Human

Entrez Gene: 15490 Mouse

Entrez Gene: 29540 Rat

Omim: 606756 Human

SwissProt: P56937 Human

SwissProt: O88736 Mouse

SwissProt: Q62904 Rat

Unigene: 492925 Human

Unigene: 12882 Mouse

Unigene: 7040 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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