产品编号 | bs-10468R-Gold |
英文名称 | Rabbit Anti-Sema3A/Gold Conjugated antibody |
中文名称 | 胶体金标记的臂板蛋白3A抗体 |
别 名 | Semaphorin 3A; Semaphorin-3A; Semaphorin-3A precursor; Semaphorin3A; SemD; Sema 3A; SEM3A_MOUSE; Coll 1; Coll1; Hsema I; Hsema III; sema domain immunoglobulin domain (Ig) short basic domain secreted (semaphorin) 3A; Sema III; SEMA1; SEMA1-PEN; SEMA3A; SEMAD; SEMAIII; SEMAL; Semaphorin III; Semaphorin like growth cone guidance homolog of chick collapsin; Semaphorin III; Semaphorin-D; Sema D. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul(10nm 15nm 35nm) |
研究领域 | 神经生物学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse, Rat, (predicted: Human, Chicken, Dog, Pig, Horse, Rabbit, Sheep, ) |
产品应用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 86kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Sema3A |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存条件 | Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles. |
产品介绍 |
background: This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. Function: Plays a role in growth cones guidance. May function to pattern sensory projections by selectively repelling axons that normally terminate dorsally. Involved in the development of the olfactory system and in neuronal control of puberty. Subunit: Interacts with PXND1. Subcellular Location: Secreted. Tissue Specificity: Expressed at relatively high levels in brain and muscle, moderate levels in lung, bursa, and heart and virtually absent in liver. Collapsin-1, -2, -3, and -5 bind to overlapping but distinct axon tracts. Similarity: Belongs to the semaphorin family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 PSI domain. Contains 1 Sema domain. Database links: Entrez Gene: 10371 Human Entrez Gene: 20346 Mouse Omim: 603961 Human SwissProt: Q14563 Human SwissProt: O08665 Mouse SwissProt: Q5BL08 Mouse Unigene: 252451 Human Unigene: 44410 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗体溶解方法 | |
2、抗体修复方式 | |
3、常用试剂的配制 | |
4、免疫组化操作步骤 | |
5、免疫组化问题解答 | |
6、Western Blotting 操作步骤 | |
7、Western Blotting 问题解答 | |
8、关于肽链的设计 | |
9、多肽的溶解与保存 | |
10、酶标抗体效价测定程序 | |