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Rabbit Anti-NPRL3/Gold Conjugated antibody (bs-19337R-Gold)
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说 明 书: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包装/询价
产品编号 bs-19337R-Gold
英文名称 Rabbit Anti-NPRL3/Gold Conjugated antibody
中文名称 胶体金标记的氮酶调节因子3样蛋白抗体
别    名 -14 gene protein; Alpha-globin regulatory element-containing gene protein; C16ORF35; CGTHBA; Conserved gene telomeric to alpha globin cluster; HS 40; MARE; Nitrogen permease regulator 3-like protein; Nitrogen permease regulator-like 3 (S. cerevisiae); NPR3; NPRL3; NPRL3_HUMAN; Protein CGTHBA; RMD11.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul(10nm  15nm  35nm
研究领域 细胞生物  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse,  (predicted: Rat, Dog, Pig, )
产品应用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 64kDa
性    状 Lyophilized or Liquid
浓    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NPRL3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存条件 Store at 2-8 ºC for 3-6 months. Avoid repeated freeze/thaw cycles.
产品介绍 Function:
As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the NPR3 family.

Database links:

Entrez Gene: 8131 Human

Entrez Gene: 17168 Mouse

Entrez Gene: 360505 Rat

Omim: 600928 Human

SwissProt: Q12980 Human

SwissProt: Q8VIJ8 Mouse

Unigene: 19699 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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