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Rabbit Anti-NFYC/Cy5.5 Conjugated antibody (bs-19231R-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-19231R-Cy5.5
英文名称 Rabbit Anti-NFYC/Cy5.5 Conjugated antibody
中文名称 Cy5.5标记的核转录因子YC抗体
别    名 CAAT box DNA binding protein subunit C; CAAT box DNA-binding protein subunit C; CBF C; CBFC; CCAAT binding factor subunit C; CCAAT transcription binding factor subunit gamma; DKFZp667G242; FLJ45775; H1TF2A; HAP5; histone H1 transcription factor large subunit 2A; HSM; NF-YC; NFYC; NFYC_HUMAN; Nuclear transcription factor Y gamma; Nuclear transcription factor Y subunit C; Nuclear transcription factor Y subunit gamma; OTTHUMP00000009207; OTTHUMP00000009208; OTTHUMP00000009209; OTTHUMP00000009210; OTTHUMP00000009211; OTTHUMP00000009212; OTTHUMP00000009213; OTTHUMP00000009215; OTTHUMP00000009217; OTTHUMP00000231028; Transactivator HSM 1/2; transactivator HSM-1; Transactivator HSM-1/2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 转录调节因子  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NFYC
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Function:
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the NFYC/HAP5 subunit family.

Database links:

Entrez Gene: 419642 Chicken

Entrez Gene: 534003 Cow

Entrez Gene: 475312 Dog

Entrez Gene: 100715361 Guinea pig

Entrez Gene: 100053895 Horse

Entrez Gene: 4802 Human

Entrez Gene: 18046 Mouse

Entrez Gene: 25337 Rat

Entrez Gene: 323445 Zebrafish

Omim: 605344 Human

SwissProt: Q5E9X1 Cow

SwissProt: Q13952 Human

SwissProt: P70353 Mouse

SwissProt: Q62725 Rat

Unigene: 713051 Human

Unigene: 435590 Mouse

Unigene: 477613 Mouse

Unigene: 1457 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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