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Rabbit Anti-Cathepsin H mini chain/BF647 Conjugated antibody (bs-10675R-BF647)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-10675R-BF647
英文名称1 Rabbit Anti-Cathepsin H mini chain/BF647 Conjugated antibody
中文名称 BF647标记的组织蛋白酶H迷你链抗体
别    名 CTSH; Cathepsin H; ACC4; ACC5; Cathepsin H mini chain; CPSB; cath-H; CH; Ctsh; CATH_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  转录调节因子  合成与降解  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 2kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cathepsin H mini chain
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in various cellular events such as peptide biosynthesis and protein degradation. The propeptide region of cathepsin H is highly homologous to other cathepsins. This region is thought to play a role in the processing of cysteine proteases. Cathepsin H is thought to be involved in several pathological conditions, including neuro degenerative disorders and cancer.

Function:
Important for the overall degradation of proteins in lysosomes.

Subunit:
Composed of a mini chain and a large chain. The large chain may be split into heavy and light chain. All chains are held together by disulfide bonds.

Subcellular Location:
Lysosome.

Similarity:
Belongs to the peptidase C1 family.

Database links:

Entrez Gene: 1512 Human

Entrez Gene: 25425 Rat

Omim: 116820 Human

SwissProt: P09668 Human

SwissProt: P00786 Rat

Unigene: 148641 Human

Unigene: 1997 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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