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Rabbit Anti-PACSIN3/APC Conjugated antibody (bs-13659R-APC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-13659R-APC
英文名称 Rabbit Anti-PACSIN3/APC Conjugated antibody
中文名称 APC标记的胞浆蛋白PACSIN3抗体
别    名 Endophilin 1; Endophilin I; FLJ17861; OTTHUMP00000234262; OTTHUMP00000234263; OTTHUMP00000234264; PACN3_HUMAN; Pacsin3; Protein kinase C and casein kinase substrate in neurons 3; Protein kinase C and casein kinase substrate in neurons protein 3; SDPIII; SH3 domain containing protein 6511; SH3 domain-containing protein 6511; syndapin III;  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  神经生物学  信号转导  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human,  (predicted: Mouse, Rat, Pig, Cow, Horse, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PACSIN3
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity).

Function:
May play a role in vesicle formation and transport.

Subcellular Location:
Cytoplasm. Cell membrane. Detected at the inner aspect of the plasma membrane in cells or myotubes.

Tissue Specificity:
Expressed in heart and skeletal muscle, lung, kidney, adrenal gland and placenta.

Post-translational modifications:
Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC).

Similarity:
Belongs to the PACSIN family.
Contains 1 FCH domain.
Contains 1 SH3 domain.

Database links:

Entrez Gene: 29763 Human

Entrez Gene: 80708 Mouse

Omim: 606513 Human

SwissProt: Q9UKS6 Human

SwissProt: Q99JB8 Mouse

Unigene: 334639 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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