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Rabbit Anti-GGT7 light chain/PE-Cy5.5 Conjugated antibody (bs-10459R-PE-Cy5.5)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-10459R-PE-Cy5.5
英文名称1 Rabbit Anti-GGT7 light chain/PE-Cy5.5 Conjugated antibody
中文名称 PE-Cy5.5标记的γ-谷氨酰转肽酶7轻链抗体
别    名 Gamma-glutamyltransferase 7 light chain; D20S101; dJ18C9.2; Gamma glutamyltransferase 4; Gamma glutamyltransferase 7; Gamma glutamyltransferase like 3; Gamma glutamyltransferase like 5; Gamma glutamyltranspeptidase 7; Gamma glutamyltranspeptidase like 3; GGT 7; GGT4; GGTL3; GGTL5; GGT7_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  干细胞  新陈代谢  跨膜蛋白  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Gamma-glutamyltransferase 7 light chain
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008].

Function:
Cleaves glutathione conjugates

Subunit:
Heterodimer composed of the light and heavy chains. The active site is located in the light chain. Isoform 3 interacts with FAM57A.

Subcellular Location:
Membrane; Single pass type II membrane protein.

Tissue Specificity:
Widely expressed, but at low level, except in the airway epithelial cells. Detected in brain, heart, kidney, liver, lung, spleen, testis and trachea.

Similarity:
Belongs to the gamma-glutamyltransferase family.

Database links:
UniProtKB/Swiss-Prot: Q9UJ14.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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