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Rabbit Anti-PCSK4/AP Conjugated antibody (bs-15501R-AP)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-15501R-AP
英文名称1 Rabbit Anti-PCSK4/AP Conjugated antibody
中文名称 碱性磷酸酶(AP)标记的原蛋白转化酶4抗体
别    名 PC4; PCSK4; PCSK4_HUMAN; Proprotein convertase 4; Proprotein convertase PC4; Proprotein convertase subtilisin/kexin type 4.   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Pig, Cow, )
产品应用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCSK4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
PCSK4 is a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in reproduction and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein (proPACAP) and pro-insulin-like growth factor II.

Function:
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Plays a role in transcriptional coactivation. May be involved in stabilizing the multiprotein transcription complex.

Subcellular Location:
Membrane; Single-pass membrane protein (Potential).

Tissue Specificity:
Placenta.

Similarity:
Belongs to the peptidase S8 family. Furin subfamily.
Contains 1 FU (furin-like) repeat.

Database links:

Entrez Gene: 54760 Human

Omim: 600487 Human

SwissProt: Q6UW60 Human

Unigene: 46884 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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