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Rabbit Anti-IL-19/BF488 Conjugated antibody (bs-10087R-BF488)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-10087R-BF488
英文名称 Rabbit Anti-IL-19/BF488 Conjugated antibody
中文名称 BF488标记的白细胞介素19抗体
别    名 Interleukin-19; IL 10C; IL 19; Interleukin 19; MDA1;ZMDA1; IL-19; Melanoma differentiation-associated protein-like protein; NG.1; IL19_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IL-19/NG.1
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq].

Function:
May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis.

Subcellular Location:
Secreted.

Similarity:
Belongs to the IL-10 family.

Database links:

Entrez Gene: 29949 Human

Entrez Gene: 329244 Mouse

Omim: 605687 Human

SwissProt: Q9UHD0 Human

SwissProt: Q8CJ70 Mouse

Unigene: 661017 Human

Unigene: 131480 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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