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Rabbit Anti-G gamma7/BF647 Conjugated antibody (bs-13246R-BF647)
~~~促销,代码KT202502A~~~
~~~促销,代码KT202502B~~~
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-13246R-BF647
英文名称 Rabbit Anti-G gamma7/BF647 Conjugated antibody
中文名称 BF647标记的G蛋白偶联受体γ7抗体
别    名 FLJ00058; GBG7_HUMAN; Gng7; GNGT7; Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-7 subunit; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 肿瘤  细胞生物  信号转导  G蛋白偶联受体  新陈代谢  G蛋白信号  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Cow, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 7kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human G gamma7
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum.

Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity).

Subunit:
G proteins are composed of 3 units, alpha, beta and gamma.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed in a variety of tissues. Down-regulated in pancreatic and esophageal cancer.

Similarity:
Belongs to the G protein gamma family.

Database links:
UniProtKB/Swiss-Prot: O60262.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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