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Rabbit Anti-FbxL4/APC Conjugated antibody (bs-13166R-APC)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-13166R-APC
英文名称 Anti-FbxL4/APC
中文名称 APC标记的F-box富含亮氨酸重复蛋白4抗体
别    名 F box and leucine rich repeat protein 4; F box protein FBL4/FBL5; F box/LRR repeat protein 4; F-box and leucine-rich repeat protein 4; F-box protein FBL 4; F-box protein FBL4/FBL5; F-box/LRR-repeat protein 4; FBL 4; FBL 5; FBL4; FBL5; Fbxl4; FBXL4_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  细胞周期蛋白  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Chicken, Cow, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FbxL4/FBL4
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 9 tandem leucine-rich repeats. [provided by RefSeq, Jul 2008].

Subunit:
Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By similarity).

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Expressed in heart, kidney, liver, lung, pancreas, and placenta, but not in skeletal muscle.

Similarity:
Contains 1 F-box domain.
Contains 9 LRR (leucine-rich) repeats.

Database links:

Entrez Gene: 26235 Human

Entrez Gene: 269514 Mouse

Entrez Gene: 100156082 Pig

Entrez Gene: 535452 Cow

Omim: 605654 Human

SwissProt: Q0VD31 Cow

SwissProt: Q9UKA2 Human

SwissProt: Q8BH70 Mouse

Unigene: 536850 Human

Unigene: 40708 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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