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Rabbit Anti-CSNK1A1L/BF488 Conjugated antibody (bs-12943R-BF488)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-12943R-BF488
英文名称1 Rabbit Anti-CSNK1A1L/BF488 Conjugated antibody
中文名称 BF488标记的酪蛋白激酶1/casein kinase Iα抗体
别    名 Casein kinase 1, alpha 1 like; casein kinase 1, alpha 1-like; Casein kinase I alpha S like; Casein kinase I isoform alpha like; CK1; CKI alpha like; MGC33182; OTTHUMP00000018267; RP11 532O21.2; KC1AL_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  信号转导  激酶和磷酸酶  细胞分化  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 (predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, )
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CSNK1A1L
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase I Alpha, I Gamma, I Delta and I Epsilon, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair, membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Casein kinase I isoform alpha-like (CSNK1A1L) is a 337 amino acid protein that shares a high degree of sequence similarity with the alpha isoform of casein kinase 1. CSNK1A1L resides in the cytoplasm and participates in the Wnt signaling pathway. By utilizing ATP within its protein kinase domain, CSNK1A1L phosphorylates a large number of proteins.

Function:
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CSNK1A1L can phosphorylate a large number of proteins and participates in Wnt signaling.

Subcellular Location:
Cytoplasmic.

Similarity:
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Contains 1 protein kinase domain

Database links:
UniProtKB/Swiss-Prot: Q8N752.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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