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Rabbit Anti-RSV Nucleoprotein/BF594 Conjugated antibody (bs-10207R-BF594)
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说 明 书: 100ul  
100ul/2980.00元
大包装/询价
产品编号 bs-10207R-BF594
英文名称 Rabbit Anti-RSV Nucleoprotein/BF594 Conjugated antibody
中文名称 BF594标记的呼吸道合胞病毒核蛋白抗体
别    名 Respiratory syncytial virus nucleoprotein; N; NCAP_HRSVA; Nucleoprotein; Protein N; Nucleocapsid protein.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 免疫学  细菌及病毒  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应
产品应用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Respiratory Syncytial Virus Nucleoprotein
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Respiratory syncytial virus (RSV) is a major cause of respiratory illness in young children. RSV infection produces a variety of signs and symptoms involving different areas of the respiratory tract, from the nose to the lungs. RSV is a negative sense, enveloped RNA virus. The virion is variable in shape and size with average diameter of between 120 and 300 nm.

Function:
Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has an helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.

Subunit:
Homomultimerizes to form the nucleocapsid. Binds to viral genomic RNA. In nucleocapsid, interacts with the protein P and thereby positions the polymerase on the template. Interacts with protein M2-1; this interaction allows the association of nucleocapsid with the matrix protein, supposely to shut down virus transcriptase activity and initiate assembly and budding.

Subcellular Location:
Virion. Host cytoplasm.

Similarity:
Belongs to the paramyxoviruses nucleocapsid family.

Database links:
UniProtKB/Swiss-Prot: P03418.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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